Hydride attack at a ferric heme–NO to give an Fe–HNO intermediate is a key step in the global N--‐cycle. We demonstrate differential reactivity when six--‐ and five--‐coordinate ferric heme--‐NO models react with hydride. Although Fe–HNO formation is thermodynamically favored from this reaction, Fe–H formation is kinetically favored for the 5C case.
Abucayon, E G.; Khade, R L.; Powell, D R.; Shaw, Michael J.; Yang, Y; and Richter-Addo, G B., "Over or Under: Hydride Attack at the Metal versus the Coordinated Nitrosyl Ligand in Ferric Nitrosyl Porphyrins." (2016). SIUE Faculty Research, Scholarship, and Creative Activity. 53.