Date of Award

Spring 5-4-2018

Document Type

DNP Project

Project Team Faculty Member

Mary Zerlan


ketamine, CRPS, complex regional pain syndrome, protocol


Complex Regional Pain Syndrome (CRPS) has been studied under different names dating back to the American Civil War. Despite being studied for over 100 years, CRPS is still not a very well understood disease process and there is no consensus on the best way to treat it (O’Connell, Wand, McAuley, Marston, & Moseley, 2016). One treatment that has shown to be effective in reducing pain scores in patients with chronic CRPS is a multiple day infusion of ketamine (Sigtermans et al., 2009). The purpose of this doctor of nursing practice project was to develop a ketamine infusion protocol for anesthesia providers at community hospital in the Midwest.

The implementation of this project was carried out through an educational inservice and evaluated using a short survey, which was filled out by the audience anonymously. Based upon the responses, it is reasonable to assume that this project can be effective in educating anesthesia providers on the topic of using ketamine infusions to treat CRPS. The protocol developed for this project can be used as a sample or guideline for facilities that are considering implementing a ketamine infusion protocol to treat CRPS. The protocol can be changed to fit the needs and constraints of a facility.

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Background_nkozul.docx (112 kB)

Problem Statement_nkozul.docx (49 kB)
Problem Statement

Clinical Relevance_nkozul.docx (58 kB)
Clinical Relevance

Review of Literature_nkozul.docx (117 kB)
Review of Literature

Theoretical Framework_nkozul.docx (56 kB)
Theoretical Framework

Methodology_nkozul.docx (110 kB)

Evaluation_Discussion_nkozul.docx (112 kB)

FinalReferences_nkozul.docx (100 kB)
Final References List

Included in

Nursing Commons



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